Dr. Xi Jiang introduced how to establish structural and functional common brain architecture and its application on modeling functional interactions of cortical gyri and sulci. He stated that Brain mapping is further defined as the study of the anatomy and function of the brain and spinal cord through the use of imaging, immunohistochemistry, molecular & optogenetics, stem cell and cellular biology, engineering (material, electrical and biomedical), neurophysiology and nanotechnology. Different data modalities map different brain tissues and structures in different scales and perspectives since the regularity (segregation and integration are two basic rules governing brain functions) and variability (existing in a variety of aspects (e.g., brain volume, cortical folding patterns, etc.). He wondered whether there is a common structural and functional cortical architecture that could be quantitatively encoded and precisely reproduced across individuals and populations? If we use imaging techniques and computational approaches curious, the answer must be Yes. Thus, in the current studies, he aimed to define and discover large-scale consistent and common brain cortical landmarks with intrinsic structural (white matter fiber connection patterns based on DTI data). DICCCOL (Dense Individualized and Common Connectivitybased Cortical Landmarks) system, which includes 358 landmarks that are present in different human brains and possess group-wise consistent white matter fiber connection patterns based on DTI data could solve the problem. Detailed information is as follows: step 1: DICCCOL landmark initialization via random initialization of cortical points; step 2: Extraction of fiber tracts connection of a landmark; step 3: Quantitative representation of fiber tracts connection pattern using ‘trace-map’ model; step 4: Landmark optimization based on maximal group-wise similarity of fiber tracts connection pattern across individuals.

The Academic Salon events were held in the development center of HR department and invited researchers with various expertise to give presentations of their latest work. This event is aimed to establish a platform for academic communication and broaden the dimensions of studies conducted in our institution.